H1N1 Influenza Center

Enrolling Pregnant Women in Research — Lessons from the H1N1 Influenza Pandemic

PERSPECTIVE
Enrolling Pregnant Women in Research — Lessons from the H1N1 Influenza Pandemic
S.F. Goldkind, L. Sahin, and B. Gallauresi

The global H1N1 influenza pandemic disproportionately affected pregnant women, drawing attention to the fact that they have always been a marginalized study population. Dr. Sara Goldkind and colleagues argue that it is imperative that pregnant women be judiciously included in research.

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More Reassuring Data on 2009 H1N1 Vaccination and Guillain-Barré Syndrome

New CDC data strengthen the evidence that the risk for Guillain-Barré syndrome (GBS) associated with the 2009 H1N1 vaccine is similar to the risk seen with seasonal flu vaccines, according to an MMWR report. (more…)

Certain H1N1 Vaccines Should Be Given by Feb. 15

All lots of Sanofi Pasteur H1N1 vaccine in prefilled syringes should be administered by February 15 because of concerns over reduced potency, the CDC reported on Wednesday. (more…)

CDC Offers Latest Estimates of H1N1 Toll

Estimates of 2009 H1N1 influenza cases in the U.S. from April 2009 to mid-January 2010 ranged widely, from 41 million to 84 million, according to the CDC. (more…)

WHO Addresses Vaccine Anaphylaxis, Drug Resistance, H1N1 Mutations

The World Health Organization has addressed several 2009 H1N1 reports that have received a lot of press attention over the past week, including post-vaccination anaphylaxis, clusters of oseltamivir resistance, and an H1N1 mutation. (more…)

Responses to 2009 H1N1 Vaccine in Children 3 to 17 Years of Age

CORRESPONDENCE
Responses to 2009 H1N1 Vaccine in Children 3 to 17 Years of Age
A. Arguedas, C. Soley, and K. Lindert

These preliminary data support the use of one 15-μg dose of 2009 H1N1 vaccine without adjuvant in children between the ages of 9 and 17 years. However, in children 3 to 8 years of age, only the 7.5-μg dose of 2009 H1N1 vaccine with adjuvant met both the immunogenicity criteria after one dose.

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Preparing for 2009 H1N1 Influenza

EDITORIAL
Preparing for 2009 H1N1 Influenza
R.P. Wenzel and M.B. Edmond

Drs. Richard Wenzel and Michael Edmond write that the 4500 deaths from 2009 H1N1 influenza are approximately 2% of the 250,000 or more deaths seen worldwide from seasonal influenza each year. Nevertheless, no one should be complacent about an unpredictable virus capable of killing children and young adults in their prime.

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Related article by the ANZIC Influenza Investigators: Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand
Related article by S. Jain and Others: Hospitalized Patients with 2009 H1N1 Influenza in the United States, April–June 2009

The Emotional Epidemiology of H1N1 Influenza Vaccination

PERSPECTIVE
The Emotional Epidemiology of H1N1 Influenza Vaccination
D. Ofri

Dr. Danielle Ofri describes the fascinating and frustrating shift in public sentiment over the course of the H1N1 epidemic.

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Online First June 29, 2009, from the New England Journal of Medicine

ORIGINAL ARTICLES
Severe Respiratory Disease Concurrent with the Circulation of H1N1 Influenza
G. Chowell and Others
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Pneumonia and Respiratory Failure from Swine-Origin Influenza A (H1N1) in Mexico
R. Perez-Padilla and Others
Full Text | PDF | Supplementary Material

CURRENT CONCEPTS
Historical Perspective — Emergence of Influenza A (H1N1) Viruses
S.M. Zimmer and D.S. Burke
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PERSPECTIVE
The Persistent Legacy of the 1918 Influenza Virus
D.M. Morens, J.K. Taubenberger, and A.S. Fauci
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CORRESPONDENCE
Spread of a Novel Influenza A (H1N1) Virus via Global Airline Transportation
K. Khan and Others
Full Text | PDF | Supplementary Material

Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in Humans
D.J. Faix, S.S. Sherman, and S.H. Waterman
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Online First May 27, 2009, from the New England Journal of Medicine

PERSPECTIVE
Managing and Reducing Uncertainty in an Emerging Influenza Pandemic
M. Lipsitch and Others
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Geographic Dependence, Surveillance, and Origins of the 2009 Influenza A (H1N1) Virus
V. Trifonov, H. Khiabanian, and R. Rabadan
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Diagnostic Testing for 2009 Pandemic Influenza A (H1N1) Virus Infection in Hospitalized Patients

Establishing a diagnosis of 2009 pandemic influenza A (H1N1) virus infection in hospitalized patients can be challenging, especially in patients presenting late in their clinical course. (more…)

H1N1 news: Jan. 19, 2010

On the White House Blog Saturday, Kathleen Sebelius encouraged Americans become a “Flu Fighter” on Facebook by installing the DHHS’s new Facebook app. “This application,” she wrote, “gives people a fun way to encourage friends and family to get vaccinated.” (1/16, The White House Blog)

About 1 in 5 Americans have been vaccinated against H1N1, according to the government’s first detailed estimates of vaccination rates. (1/15, AP)