H1N1 Influenza Center

From the Publishers of the New England Journal of Medicine

New England Journal of Medicine rss

Antiviral Treatment for Patients Hospitalized with 2009 Pandemic Influenza A (H1N1)(2)

November 18, 2009

With the 2009 H1N1 pandemic well under way, many clinicians are providing care to patients with influenza. Previously, although antiviral treatment was recommended,1,2 clinicians may not always have prescribed it to patients hospitalized with seasonal influenza, perhaps because of a perception that antiviral treatment had limited benefit.

Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in Humans

CORRESPONDENCE
Rapid-Test Sensitivity for Novel Swine-Origin Influenza A (H1N1) Virus in Humans
C.C. Blyth, J.R. Iredell, and D.E. Dwyer
Rapid antigen tests, as compared with RT-PCR assays, had poor sensitivity to the 2009 influenza A (H1N1) virus in 21 patients with severe infection and acute lung injury that required mechanical ventilation.
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Emergence of Oseltamivir-Resistant Pandemic H1N1 Virus during Prophylaxis

CORRESPONDENCE
Emergence of Oseltamivir-Resistant Pandemic H1N1 Virus during Prophylaxis
D.N. Fisman and Others
The results indicate that a neuraminidase mutation (H275Y) is associated with oseltamivir resistance not only in seasonal H1N1 and avian H5N1 viruses but now also in 2009 pandemic H1N1 strains.
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Older Age and a Reduced Likelihood of 2009 H1N1 Virus Infection

CORRESPONDENCE
Older Age and a Reduced Likelihood of 2009 H1N1 Virus Infection
D.N. Fisman and Others
Among persons who were at risk for infection with 2009 H1N1 virus, being born before 1957 was associated with a lower infection risk.
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