H1N1 Influenza Center

H1N1 Influenza Center Archive

lscott — Thu, 01 Jul 2010 20:47:02 +0000

This H1N1 Influenza Center contains content and data that were posted during the 2009–2010 H1N1 outbreak.
For more recent information, please search on NEJM.org and JWatch.org.

Enrolling Pregnant Women in Research — Lessons from the H1N1 Influenza Pandemic

NEJM Editors — Wed, 16 Jun 2010 21:05:12 +0000

PERSPECTIVE
Enrolling Pregnant Women in Research — Lessons from the H1N1 Influenza Pandemic
S.F. Goldkind, L. Sahin, and B. Gallauresi

The global H1N1 influenza pandemic disproportionately affected pregnant women, drawing attention to the fact that they have always been a marginalized study population. Dr. Sara Goldkind and colleagues argue that it is imperative that pregnant women be judiciously included in research.

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2009 H1N1 Virus Transmission and Outbreaks

NEJM Editors — Wed, 09 Jun 2010 21:05:42 +0000

ORIGINAL ARTICLES
Oseltamivir Ring Prophylaxis for Containment of 2009 H1N1 Influenza Outbreaks
V.J. Lee and Others

Ring prophylaxis (geographically targeted containment by means of prophylaxis) with oseltamivir was shown to substantially curtail four outbreaks involving 1175 personnel in the Singapore military.

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Comparative Epidemiology of Pandemic and Seasonal Influenza A in Households
B.J. Cowling and Others

In this study from Hong Kong, investigators show that the pandemic and seasonal influenza A viruses behave in a similar manner with respect to the pattern of illness, viral shedding, and secondary attack rates.

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EDITORIAL
2009 H1N1 Virus Transmission and Outbreaks
T.M. Uyeki

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More Reassuring Data on 2009 H1N1 Vaccination and Guillain-Barré Syndrome

Journal Watch Editors — Thu, 03 Jun 2010 18:06:11 +0000

New CDC data strengthen the evidence that the risk for Guillain-Barré syndrome (GBS) associated with the 2009 H1N1 vaccine is similar to the risk seen with seasonal flu vaccines, according to an MMWR report.

The CDC’s analysis of data from October 2009 through March 2010 found that the incidence of GBS was 1.92 per 100,000 person-years among vaccinated individuals and 1.21 per 100,000 person-years among the unvaccinated. If final data confirm this finding, the CDC says, then this would translate to 0.8 excess GBS cases for every 1 million vaccinations — a rate comparable to that found with seasonal flu vaccination.

Symptom Patterns in 2009 Pandemic Influenza vs. Seasonal Influenza

Journal Watch Editors — Thu, 03 Jun 2010 01:48:04 +0000

A study conducted in Singapore showed significant differences between these illnesses. (more…)

The Public’s Response to the 2009 H1N1 Influenza Pandemic

NEJM Editors — Wed, 19 May 2010 21:05:36 +0000

PERSPECTIVE
The Public’s Response to the 2009 H1N1 Influenza Pandemic
G.K. SteelFisher and Others

Gillian SteelFisher and colleagues examined the public’s response to the 2009 H1N1 pandemic through a comprehensive review of data from national public opinion polls and surveys. They present a range of findings.

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Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection

NEJM Editors — Wed, 05 May 2010 21:05:38 +0000

MEDICAL PROGRESS
Clinical Aspects of Pandemic 2009 Influenza A (H1N1) Virus Infection
Writing Committee of the WHO Consultation on Clinical Aspects of Pandemic (H1N1) 2009 Influenza

Illness caused by the 2009 H1N1 virus has occurred in almost all countries, with more than 16,000 deaths from laboratory-confirmed cases reported to the WHO. This review by WHO experts summarizes the virologic, epidemiologic, and clinical data on the 2009 H1N1 virus and assesses future directions.

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Information Technology and Global Surveillance of Cases of 2009 H1N1 Influenza

NEJM Editors — Wed, 05 May 2010 21:05:01 +0000

SPECIAL REPORT
Information Technology and Global Surveillance of Cases of 2009 H1N1 Influenza
J.S. Brownstein and Others

Although formal reporting, surveillance, and response structures remain essential to protecting public health, a new generation of freely accessible, online, and real-time informatics tools for disease tracking are expanding the ability of public health professionals to detect weak signals across borders and to raise earlier warnings of emerging disease threats.

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Georgia Seeing Increase in H1N1 Hospitalizations

Journal Watch Editors — Tue, 30 Mar 2010 12:47:55 +0000

The CDC reports an increase in H1N1-related hospitalizations in Georgia and a few other southeastern states, particularly among adults with certain chronic conditions (e.g., diabetes, COPD, heart disease).

In the past week, Georgia has reported 40 hospitalizations with laboratory-confirmed 2009 H1N1 illness. This is the third straight week that the state has had the highest number of H1N1 hospitalizations in the country, and the number of hospitalizations appears to be rising.

Alabama and South Carolina are also reporting regional H1N1 activity, while eight other states are seeing local activity.

Federal health officials again urged adults, especially those with underlying health conditions, to get vaccinated against H1N1.

A Critical Look at Flu Vaccine Studies

Journal Watch Editors — Mon, 22 Feb 2010 18:10:25 +0000

The vaccine can give the impression of preventing death even when no influenza is in sight. (more…)