H1N1 Influenza Center

From the Publishers of the New England Journal of Medicine

Estimates of Flu’s Toll; Seasonal Vaccine Not Effective Against 2009 H1N1 Estimates of Flu’s Toll; Seasonal Vaccine Not Effective Against 2009 H1N1 Estimates of Flu’s Toll; Seasonal Vaccine Not Effective Against 2009 H1N1

Reports on 2009 H1N1 influenza in the U.S. will now use estimates from the CDC’s Emerging Infection Program, rather than counting only laboratory-confirmed cases, according to a CDC news briefing.

The new estimates for the first 6 months of the pandemic — from mid-April to mid-October — find that:

  • Roughly 22 million people in the U.S. became ill from the virus.
  • Nearly 100,000 were hospitalized.
  • Some 3900 died, including an estimated 540 children under 18; some 2900 adults between 18 and 64; and 440 elderly.

This week’s MMWR carries a CDC analysis concluding that the seasonal trivalent vaccine offers no protection from — or increased risk for — 2009 H1N1 disease. An additional surveillance article on the pandemic notes that “severe outcomes among children … continue to be prominent” and provide support for the recommendation that those aged 6 months to 24 years be targeted for vaccination.

Also on Thursday, the FDA granted accelerated approval for the use of CSL Limited’s 2009 H1N1 influenza vaccine in children 6 months and up. The vaccine had previously been indicated for adults


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