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Intravenous Zanamivir for Oseltamivir-Resistant 2009 H1N1 Influenza
CORRESPONDENCE Intravenous Zanamivir for Oseltamivir-Resistant 2009 H1N1 Influenza A.H. Gaur and Others The authors detected oseltamivir-resistant H1N1 virus in a 10-year-old girl. She was successfully treated with intravenous zanamivir. Full Text | PDF | Supplementary Material
A Community Cluster of Oseltamivir-Resistant Cases of 2009 H1N1 Influenza
CORRESPONDENCE A Community Cluster of Oseltamivir-Resistant Cases of 2009 H1N1 Influenza L.Q. Mai and Others The authors report on a cluster of seven cases of oseltamivir-resistant 2009 H1N1 infection in Vietnam. Full Text | PDF | Supplementary Material
H1N1 news: Nov. 30, 2009
The WHO said last week that the recent H1N1 mutation that caused oseltamivir resistance in approximately 75 people is not “a major shift” in the virus. (11/28, NYT) Five people died from H1N1 during the hajj, the largest annual gathering in the world which concluded Sunday. (11/29, AP)
WHO Addresses Vaccine Anaphylaxis, Drug Resistance, H1N1 Mutations
The World Health Organization has addressed several 2009 H1N1 reports that have received a lot of press attention over the past week, including post-vaccination anaphylaxis, clusters of oseltamivir resistance, and an H1N1 mutation.
H1N1 news: Nov. 25, 2009
The CDC said Wednesday they are seeing “a worrying pattern of serious bacterial infections” among some H1N1 patients. (11/25, Reuters) The WHO is looking into reports from Britain and the U.S. that H1N1 may have developed resistance to oseltamivir in those with severely suppressed immune systems, according to a WHO spokesman. (11/25, AP) GSK has [...]
H1N1 News: Nov. 16, 2009
Two patients with oseltamivir-resistant H1N1 in Scotland have fully recovered. (11/16, The Times, London) Dr. Margaret Hamburg last week defended the FDA’s decision to not use adjuvanted H1N1 vaccines. (11/12, Reuters)
Emergence of Oseltamivir-Resistant Pandemic H1N1 Virus during Prophylaxis
CORRESPONDENCE Emergence of Oseltamivir-Resistant Pandemic H1N1 Virus during Prophylaxis M. Baz and Others The results indicate that a neuraminidase mutation (H275Y) is associated with oseltamivir resistance not only in seasonal H1N1 and avian H5N1 viruses but now also in 2009 pandemic H1N1 strains. Full Text | PDF
H1N1 Update: Oseltamivir Resistance and Antiviral Use
The CDC reports oseltamivir-resistant 2009 pandemic influenza A (H1N1) virus infection in two children who received prophylaxis and provides revised recommendations for antiviral use during the 2009 flu season. READ MORE…
H1N1 Update for July 13, 2009: Severe Disease in Obese Patients, Resistance Brief
The CDC reports that of 10 patients admitted to intensive care with confirmed H1N1 in Michigan, 9 were obese (BMI, 30 or above) and 7 were severely obese (BMI, 40 or above). Separately, the WHO reported a third cases of documented oseltamivir-resistant H1N1 infection, leading the CDC to reiterate its call to limit antiviral use [...]
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