H1N1 Influenza Center

From the Publishers of the New England Journal of Medicine

Tag Archive for ‘zanamivir’

Antiflu Arsenal Might Be Weaker Than You Think

A Cochrane Collaborative analysis found little evidence to support routine neuraminidase use in healthy adults. (more…)

Intravenous Zanamivir for Oseltamivir-Resistant 2009 H1N1 Influenza

CORRESPONDENCE Intravenous Zanamivir for Oseltamivir-Resistant 2009 H1N1 Influenza A.H. Gaur and Others The authors detected oseltamivir-resistant H1N1 virus in a 10-year-old girl. She was successfully treated with intravenous zanamivir. Full Text | PDF | Supplementary Material

Neuraminidase Inhibitors Have Only ‘Modest Effectiveness’ in Otherwise Healthy Adults with Flu

Oseltamivir and zanamivir “have modest effectiveness against the symptoms of influenza in otherwise healthy adults,” according to a BMJ analysis published online.

Emergence of Oseltamivir-Resistant Pandemic H1N1 Virus during Prophylaxis

CORRESPONDENCE Emergence of Oseltamivir-Resistant Pandemic H1N1 Virus during Prophylaxis M. Baz and Others The results indicate that a neuraminidase mutation (H275Y) is associated with oseltamivir resistance not only in seasonal H1N1 and avian H5N1 viruses but now also in 2009 pandemic H1N1 strains. Full Text | PDF